PNRC1 Antibody

Code CSB-PA018289GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
PNRC1
Alternative Names
PNRC1 antibody; PROL2 antibody; Proline-rich nuclear receptor coactivator 1 antibody; Proline-rich protein 2 antibody; Protein B4-2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human PNRC1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Nuclear receptor coactivator. May play a role in signal transduction.
Gene References into Functions
  1. PNRC and Grb2, by interacting with each other, can suppress nuclear receptor-mediated regulation and growth factor-mediated regulation in human breast tissue PMID: 15122321
  2. Functional analysis of the 5' flanking region of the human PNRC gene by deletion mutagenesis, transient transfection and luciferase assays revealed that the -123/+27 region is the minimal promoter of the human PNRC gene. PMID: 18281297
  3. Three human PNRC splicing variants designated PNRC1c, PNRC1d and PNRC1f, are identified. PMID: 18703122
  4. RFX1 specifically bind to promoter region and negatively regulate the transcription of the human PNRC gene. PMID: 19334528
Subcellular Location
Nucleus.
Protein Families
PNRC family, PNRC1 subfamily
Tissue Specificity
Expressed in liver, lung, fat and NK/T cells.
Database Links

HGNC: 17278

OMIM: 606714

KEGG: hsa:10957

STRING: 9606.ENSP00000336931

UniGene: Hs.75969

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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