PODXL2 Antibody

Code CSB-PA018294GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
PODXL2
Alternative Names
PODXL2 antibody; UNQ1861/PRO3742 antibody; Podocalyxin-like protein 2 antibody; Endoglycan antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human PODXL2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L-selectins.
Gene References into Functions
  1. endoglycan functions as an L-selectin ligand through modification with tyrosine sulfation and sialyl Lewis x PMID: 12889478
  2. findings indicate that endoglycan can function as a ligand for the vascular selectins. PMID: 18606703
Subcellular Location
Membrane; Single-pass type I membrane protein.
Protein Families
Podocalyxin family
Tissue Specificity
Expressed in T-cells, B-cells and monocytes. Expression is higher on memory and germinal center cells than on naive B-cells (at protein level). Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in live
Database Links

HGNC: 17936

OMIM: 616627

KEGG: hsa:50512

STRING: 9606.ENSP00000345359

UniGene: Hs.591290

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