POGZ Antibody

Code CSB-PA018299LA01HU
Size US$166
Order now
Image
  • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA018299LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA018299LA01HU at dilution of 1:100

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) POGZ Polyclonal antibody
Uniprot No.
Target Names
POGZ
Alternative Names
KIAA0461 antibody; MGC71543 antibody; Pogo transposable element with ZNF domain antibody; POGZ antibody; POGZ_HUMAN antibody; putative protein product of Nbla00003 antibody; SUHW5 antibody; suppressor of hairy wing homolog antibody; Suppressor of hairy wing homolog 5 antibody; Zinc finger protein 280E antibody; Zinc finger protein 635 antibody; ZNF280E antibody; ZNF635 antibody; ZNF635M antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Pogo transposable element with ZNF domain protein (1-300AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The POGZ Antibody (Product code: CSB-PA018299LA01HU) is Non-conjugated. For POGZ Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA018299LB01HU POGZ Antibody, HRP conjugated ELISA
FITC CSB-PA018299LC01HU POGZ Antibody, FITC conjugated
Biotin CSB-PA018299LD01HU POGZ Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms.
Gene References into Functions
  1. In silico analysis and western blotting revealed this frameshift mutation generating truncated protein in peripheral blood lymphocytes, and this may disrupt several important domains of POGZ gene. Our finding broadens the spectrum of POGZ mutations and may help to understand the molecular basis of Intellectual disability (ID) and aid genetic counseling. PMID: 26763879
  2. Data suggest that loss of function variants in POGZ lead to an identifiable syndrome of neurodevelopmental disorders with specific phenotypic traits including intellectual disability. PMID: 26739615
  3. We find that POGZ is constitutively expressed across most tissues and has significantly higher levels of expression in the cerebellum and the pituitary gland. Disruption of POGZ is associated with intellectual disability and autism spectrum disorders PMID: 26942287
  4. The results reveal POGZ as an essential protein that links HP1alpha dissociation with Aurora B kinase activation during mitosis. PMID: 20562864
Involvement in disease
White-Sutton syndrome (WHSUS)
Subcellular Location
Nucleus. Chromosome. Cytoplasm.
Database Links

HGNC: 18801

OMIM: 614787

KEGG: hsa:23126

STRING: 9606.ENSP00000271715

UniGene: Hs.489873

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*