POLR1E Antibody

Code CSB-PA018326GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
POLR1E
Alternative Names
A49 antibody; DNA directed RNA polymerase I subunit RPA49 antibody; DNA-directed RNA polymerase I subunit E antibody; DNA-directed RNA polymerase I subunit RPA49 antibody; FLJ 13390 antibody; FLJ13970 antibody; PAF53 antibody; POLR 1 E antibody; POLR1E antibody; Polymerase (RNA) I associated factor 1 antibody; Polymerase (RNA) I polypeptide E antibody; Polymerase (RNA) I polypeptide E, 53kDa antibody; PRAF1 antibody; RNA polymerase I associated factor 1 antibody; RNA polymerase I associated factor 53 antibody; RNA polymerase I polypeptide E antibody; RNA polymerase I subunit A49 antibody; RNA polymerase I-associated factor 1 antibody; RNA polymerase I-associated factor 53 antibody; RP11405L18.3 antibody; RPA49_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human POLR1E
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF.
Gene References into Functions
  1. Nucleolar detention requires binding of SIRT7 to nascent pre-rRNA, linking the spatial distribution of SIRT7 and deacetylation of PAF53 to ongoing transcription. PMID: 24207024
Subcellular Location
Nucleus, nucleolus.
Protein Families
Eukaryotic RPA49/POLR1E RNA polymerase subunit family
Database Links

HGNC: 17631

KEGG: hsa:64425

STRING: 9606.ENSP00000367029

UniGene: Hs.591087

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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