POLR2D Antibody, Biotin conjugated

Datasheet

Code	CSB-PA018331LD01HU
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) POLR2D Polyclonal antibody

Uniprot No.

O15514

Target Names

POLR2D

Alternative Names

DNA directed RNA polymerase II 16 kDa polypeptide antibody; DNA directed RNA polymerase II subunit D antibody; DNA directed RNA polymerase II subunit RPB4 antibody; DNA-directed RNA polymerase II 16 kDa polypeptide antibody; DNA-directed RNA polymerase II subunit D antibody; DNA-directed RNA polymerase II subunit rpb4 antibody; HSRBP4 antibody; HSRPB4 antibody; polr2d antibody; polymerase RNA II DNA directed polypeptide D antibody; RBP4 antibody; RNA polymerase II 16 kDa subunit antibody; RNA polymerase II subunit B4 antibody; RNA polymerase II subunit D antibody; RNA polymerase II subunit hsRBP4 antibody; RPB16 antibody; RPB4_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human DNA-directed RNA polymerase II subunit RPB4 protein (1-142AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA.

Gene References into Functions

Identification of the RNA binding region of Rpb4. PMID: 16282592

Subcellular Location

Nucleus.

Protein Families

Eukaryotic RPB4 RNA polymerase subunit family

Database Links

HGNC: 9191

OMIM: 606017

KEGG: hsa:5433

STRING: 9606.ENSP00000272645

UniGene: Hs.715348

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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