POLR3F Antibody, FITC conjugated

Datasheet

Code	CSB-PA884440LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) POLR3F Polyclonal antibody

Uniprot No.

Q9H1D9

Target Names

POLR3F

Alternative Names

DNA directed RNA polymerase III 39 kDa polypeptide antibody; DNA directed RNA polymerase III 39 kDa polypeptide F antibody; DNA directed RNA polymerase III subunit F antibody; DNA directed RNA polymerase III subunit RPC6 antibody; DNA directed RNA polymerases III 39 kDa polypeptide antibody; DNA-directed RNA polymerase III subunit F antibody; DNA-directed RNA polymerase III subunit RPC6 antibody; MGC13517 antibody; Polr3f antibody; Polymerase (RNA) III (DNA directed) polypeptide F antibody; RNA polymerase III 39 kDa subunit antibody; RNA polymerase III C39 subunit antibody; RNA polymerase III subunit C6 antibody; RPC 39 antibody; RPC 6 antibody; RPC39 antibody; RPC6 antibody; RPC6_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human DNA-directed RNA polymerase III subunit RPC6 protein (1-270AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. Preferentially binds double-stranded DNA (dsDNA).

Subcellular Location

Nucleus.

Protein Families

Eukaryotic RPC34/RPC39 RNA polymerase subunit family

Database Links

HGNC: 15763

OMIM: 617455

KEGG: hsa:10621

STRING: 9606.ENSP00000366828

UniGene: Hs.472227

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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