POLR3F Antibody

Code CSB-PA018348GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
POLR3F
Alternative Names
DNA directed RNA polymerase III 39 kDa polypeptide antibody; DNA directed RNA polymerase III 39 kDa polypeptide F antibody; DNA directed RNA polymerase III subunit F antibody; DNA directed RNA polymerase III subunit RPC6 antibody; DNA directed RNA polymerases III 39 kDa polypeptide antibody; DNA-directed RNA polymerase III subunit F antibody; DNA-directed RNA polymerase III subunit RPC6 antibody; MGC13517 antibody; Polr3f antibody; Polymerase (RNA) III (DNA directed) polypeptide F antibody; RNA polymerase III 39 kDa subunit antibody; RNA polymerase III C39 subunit antibody; RNA polymerase III subunit C6 antibody; RPC 39 antibody; RPC 6 antibody; RPC39 antibody; RPC6 antibody; RPC6_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human POLR3F
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. Preferentially binds double-stranded DNA (dsDNA).
Subcellular Location
Nucleus.
Protein Families
Eukaryotic RPC34/RPC39 RNA polymerase subunit family
Database Links

HGNC: 15763

OMIM: 617455

KEGG: hsa:10621

STRING: 9606.ENSP00000366828

UniGene: Hs.472227

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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