PPFIBP2 Antibody, FITC conjugated

Code CSB-PA847688LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PPFIBP2 Polyclonal antibody
Uniprot No.
Target Names
PPFIBP2
Alternative Names
PPFIBP2 antibody; Liprin-beta-2 antibody; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2 antibody; PTPRF-interacting protein-binding protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Liprin-beta-2 protein (101-400AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
Gene References into Functions
  1. Analysis of the role of liprin-beta1 and liprin-beta2 has shown that while liprin-beta1 contributes positively to tumour cell motility in vitro; liprin-beta2 has a negative effect on both cell motility and invasion. PMID: 26663347
  2. rs12791447 is associated with prostate cancer susceptibility in Asians. mRNA levels of PPFIBP2 are differentially expressed in prostate tumours and paired normal tissues. PMID: 26443449
  3. Knockdown of either Rab17 or liprin-beta2 restores invasiveness of ERK2-depleted cells, indicating that ERK2 drives invasion of MDA-MB-231 cells by suppressing expression of these genes. PMID: 22328529
  4. analysis of crystal structure of the central coiled-coil domain from human liprin-beta2 PMID: 21462929
Protein Families
Liprin family, Liprin-beta subfamily
Tissue Specificity
Widely expressed.
Database Links

HGNC: 9250

OMIM: 603142

KEGG: hsa:8495

STRING: 9606.ENSP00000299492

UniGene: Hs.655714

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