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PPFIBP2 Antibody, HRP conjugated

Datasheet
Code CSB-PA847688LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PPFIBP2 Polyclonal antibody
Uniprot No.
Q8ND30
Target Names
PPFIBP2
Alternative Names
PPFIBP2 antibody; Liprin-beta-2 antibody; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2 antibody; PTPRF-interacting protein-binding protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Liprin-beta-2 protein (101-400AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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PPFIBP2 Antibodies

PPFIBP2 Proteins

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Target Background

Function
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
Gene References into Functions
  1. Analysis of the role of liprin-beta1 and liprin-beta2 has shown that while liprin-beta1 contributes positively to tumour cell motility in vitro; liprin-beta2 has a negative effect on both cell motility and invasion. PMID: 26663347
  2. rs12791447 is associated with prostate cancer susceptibility in Asians. mRNA levels of PPFIBP2 are differentially expressed in prostate tumours and paired normal tissues. PMID: 26443449
  3. Knockdown of either Rab17 or liprin-beta2 restores invasiveness of ERK2-depleted cells, indicating that ERK2 drives invasion of MDA-MB-231 cells by suppressing expression of these genes. PMID: 22328529
  4. analysis of crystal structure of the central coiled-coil domain from human liprin-beta2 PMID: 21462929
Protein Families
Liprin family, Liprin-beta subfamily
Tissue Specificity
Widely expressed.
Database Links

HGNC: 9250

OMIM: 603142

KEGG: hsa:8495

STRING: 9606.ENSP00000299492

UniGene: Hs.655714

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