PLPBP Antibody

Datasheet

Code	CSB-PA018755LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA018755LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA018755LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PLPBP Polyclonal antibody

Uniprot No.

O94903

Target Names

PLPBP

Alternative Names

FLJ11861 antibody; Proline synthase co-transcribed bacterial homolog protein antibody; Proline synthetase co transcribed bacterial homolog antibody; Proline synthetase co transcribed homolog (bacterial) antibody; PROSC antibody; PROSC_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Pyridoxal phosphate homeostasis protein (1-275AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PLPBP Antibody (Product code: CSB-PA018755LA01HU) is Non-conjugated. For PLPBP Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA018755LB01HU	PLPBP Antibody, HRP conjugated	ELISA
FITC	CSB-PA018755LC01HU	PLPBP Antibody, FITC conjugated
Biotin	CSB-PA018755LD01HU	PLPBP Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

Gene References into Functions

We therefore confirm PROSC as a novel gene for vitamin-B6-dependent epilepsy and delineate a non-specific plasma vitamin B6 profile under pyridoxine treatment. PMID: 28391250
Exploiting the universality of the Synechococcus elongatus COG0325 (PiPY) functions, it has been used in site-directed mutagenesis studies to shed light on disease causation by epilepsy-associated mutations in the human COG0325 gene PROSC. PMID: 28914444
studies suggest that PROSC is involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate, supplying this cofactor to apoenzymes while minimizing any toxic side reactions PMID: 27912044

Involvement in disease

Epilepsy, early-onset, vitamin B6-dependent (EPVB6D)

Protein Families

Pyridoxal phosphate-binding protein YggS/PROSC family

Tissue Specificity

Ubiquitous.

Database Links

HGNC: 9457

OMIM: 604436

KEGG: hsa:11212

STRING: 9606.ENSP00000333551

UniGene: Hs.304792

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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