PRPS2 Antibody, Biotin conjugated

Code CSB-PA018779LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PRPS2 Polyclonal antibody
Uniprot No.
Target Names
PRPS2
Alternative Names
EC 2.7.6.1 antibody; Phosphoribosyl pyrophosphate synthase II antibody; phosphoribosyl pyrophosphate synthetase 2 antibody; Phosphoribosyl pyrophosphate synthetase II antibody; PPRibP antibody; Prps2 antibody; PRPS2_HUMAN antibody; PRS II antibody; PRS-II antibody; Ribose phosphate pyrophosphokinase II antibody; Ribose-phosphate pyrophosphokinase 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ribose-phosphate pyrophosphokinase 2 protein (11-106AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
Gene References into Functions
  1. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. PMID: 26004865
  2. Meta-analysis of genome-wide association studies identifies a novel variant in PRPS2 on Xp22.3 as susceptibility locus for systemic lupus erythematosus. PMID: 25149475
  3. Analysis of in vivo C-MYC interactions with TS, IMPDH2 and PRPS2 genes confirmed that they are direct C-MYC targets. PMID: 18677108
Protein Families
Ribose-phosphate pyrophosphokinase family
Database Links

HGNC: 9465

OMIM: 311860

KEGG: hsa:5634

STRING: 9606.ENSP00000381504

UniGene: Hs.654581

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