PRPS2 Antibody, FITC conjugated

Code CSB-PA018779LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PRPS2 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
EC 2.7.6.1 antibody; Phosphoribosyl pyrophosphate synthase II antibody; phosphoribosyl pyrophosphate synthetase 2 antibody; Phosphoribosyl pyrophosphate synthetase II antibody; PPRibP antibody; Prps2 antibody; PRPS2_HUMAN antibody; PRS II antibody; PRS-II antibody; Ribose phosphate pyrophosphokinase II antibody; Ribose-phosphate pyrophosphokinase 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ribose-phosphate pyrophosphokinase 2 protein (11-106AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
Gene References into Functions
  1. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. PMID: 26004865
  2. Meta-analysis of genome-wide association studies identifies a novel variant in PRPS2 on Xp22.3 as susceptibility locus for systemic lupus erythematosus. PMID: 25149475
  3. Analysis of in vivo C-MYC interactions with TS, IMPDH2 and PRPS2 genes confirmed that they are direct C-MYC targets. PMID: 18677108
Protein Families
Ribose-phosphate pyrophosphokinase family
Database Links

HGNC: 9465

OMIM: 311860

KEGG: hsa:5634

STRING: 9606.ENSP00000381504

UniGene: Hs.654581

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