PSMC4 Antibody, Biotin conjugated

1. This study demonstrated that particular distribution for HSC70 and PSMC4 in the cytoplasm and accumulation within Lewy body in the dopaminergic neurons of the substantia nigra in Parkinson patients. PMID: 29218503
2. Structural mechanism for nucleotide-driven remodeling of RPT3 and its homologs in the activated human 26S proteasome has been reported. PMID: 29636472
3. Site-specific Rpt3 phosphorylation by DYRK2 controls cell proliferation and tumorigenesis in breast neoplasms. PMID: 26655835
4. Saquinavir-NO inhibits activation of S6 protein in androgen-dependent prostate cancer cells. PMID: 22370480
5. The proposed TRAP1 network has an impact in vivo, as it is conserved in human colorectal cancers, is controlled by ER-localized TRAP1 interacting with TBP7 and provides a novel model of the ER-mitochondria crosstalk. PMID: 21979464
6. C terminus of Rpt3, an ATPase subunit of PA700 (19 S) regulatory complex, is essential for 26 S proteasome assembly but not for activation PMID: 20937828
7. interacts with gankyrin through C-terminal 78 amino acids PMID: 11779854
8. a novel specific interaction of synphilin-1 with the regulatory proteasomal protein S6 ATPase (tbp7) in aggresome-like intracytoplasmic inclusions PMID: 17327361
9. An insertion/deletion variant in intron 5 of the S6 ATPase gene was more frequent in German Parkinson's disease patients compared to controls PMID: 18446261

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HGNC: 9551

OMIM: 602707

KEGG: hsa:5704

STRING: 9606.ENSP00000157812

UniGene: Hs.211594