PSMD6 Antibody

Code CSB-PA643972
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA643972(PSMD6 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA643972(PSMD6 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: K562 cells, mouse heart tissue, MCF7 cells, Primary antibody: CSB-PA643972(PSMD6 Antibody) at dilution 1/900, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Product Details

Uniprot No.
Target Names
PSMD6
Alternative Names
26S proteasome non-ATPase regulatory subunit 6 antibody; 26S proteasome regulatory subunit RPN7 antibody; 26S proteasome regulatory subunit S10 antibody; Breast cancer-associated protein SGA-113M antibody; KIAA0107 antibody; p42A antibody; P44S10 antibody; PFAAP4 antibody; Phosphonoformate immuno-associated protein 4 antibody; Proteasome (prosome; macropain) 26S subunit; non-ATPase; 6 antibody; Proteasome regulatory particle subunit p44S10 antibody; PSMD6 antibody; PSMD6_HUMAN antibody; Rpn7 antibody; S10 antibody; SGA-113M antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide of Human PSMD6
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:10000
WB 1:500-1:2000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Gene References into Functions
  1. Suggest AK124742 and PSMD6 as a new lncRNA-messenger RNA gene pair in human cumulus cells that may be considered as potential biomarkers to aid embryo selection. PMID: 25670720
  2. we observed that the PSMD6 variant rs831571 might be associated with the therapeutic efficacy of rosiglitazone and repaglinide in Chinese patients with type 2 diabetes. PMID: 26024304
  3. interaction of Rpn7 with DNA damage response foci in situ mediates the protection of DNA damage foci from premature resolution. PMID: 22473755
Protein Families
Proteasome subunit S10 family
Database Links

HGNC: 9564

OMIM: 617857

KEGG: hsa:9861

STRING: 9606.ENSP00000295901

UniGene: Hs.152536

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