PSMD7 Antibody, Biotin conjugated

Code CSB-PA018912LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PSMD7 Polyclonal antibody
Uniprot No.
Target Names
PSMD7
Alternative Names
26S proteasome non ATPase regulatory subunit 7 antibody; 26S proteasome non-ATPase regulatory subunit 7 antibody; 26S proteasome regulatory subunit RPN8 antibody; 26S proteasome regulatory subunit S12 antibody; integration site gene; mouse; homolog of antibody; Moloney leukemia virus 34 proviral antibody; Moloney leukemia virus 34 proviral integration antibody; MOV34 antibody; Mov34 homolog antibody; Mov34 protein homolog antibody; MOV34L antibody; P40 antibody; Proteasome (prosome; macropain) 26S subunit; non ATPase 7 antibody; Proteasome (prosome; macropain) 26S subunit; non ATPase; 7 (Mov34 homolog) antibody; Proteasome 26S S12 antibody; Proteasome 26S subunit; no-ATPase; 7 antibody; Proteasome subunit p40 antibody; PSD7_HUMAN antibody; PSMD 7 antibody; PSMD7 antibody; Rpn8 antibody; S12 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human 26S proteasome non-ATPase regulatory subunit 7 protein (1-324AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Gene References into Functions
  1. SNP rs17336700 of a non-MHC ubiquitin-proteasome subunit PSMD7 is significantly associated with ankylosing spondylitis in Chinese population and the mRNA level of the PSMD7 gene in liver tissue increased when the rs17336700 C allele was present. PMID: 20643764
  2. hVIP is a member of the complex array of nucleocytoplasmic shuttling proteins that are regulated by HIV infection and glucocorticoids PMID: 12237292
  3. data suggest a differential nuclear function of modified and unmodified S12 in cancer PMID: 15221960
  4. MPN domain of Mov34 is highly resistant to proteolysis PMID: 16842755
  5. although the MPN domain of Mov34 shows a typical metalloprotease fold, it is unable to coordinate a metal ion. PMID: 17559875

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Protein Families
Peptidase M67A family
Database Links

HGNC: 9565

OMIM: 157970

KEGG: hsa:5713

STRING: 9606.ENSP00000219313

UniGene: Hs.440604

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