PTBP3 Antibody, Biotin conjugated

Datasheet
Code CSB-PA020060ND01HU
Size US$299
Uniprot No. O95758
Immunogen Recombinant Human Polypyrimidine tract-binding protein 3 protein (37-55AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1), PTBP3, ROD1
Immunogen Species Human
Protocols ELISA Protocol
Research Area Epigenetics and Nuclear Signaling
Target Names PTBP3
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).
Tissue Specificity Expressed in several hematopoietic cell lines examined.
Database Links

HGNC: 10253

OMIM: 607527

KEGG: hsa:9991

STRING: 9606.ENSP00000334499

UniGene: Hs.269988

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