TEP1 Antibody, HRP conjugated

Code CSB-PA18049B0Rb
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TEP1 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
TEP1 antibody; TLP1 antibody; TP1 antibody; Telomerase protein component 1 antibody; Telomerase-associated protein 1 antibody; Telomerase protein 1 antibody; p240 antibody; p80 telomerase homolog antibody
Raised in
Species Reactivity
Recombinant Human Telomerase protein component 1 protein (2-226AA)
Immunogen Species
Homo sapiens (Human)
Purification Method
>95%, Protein G purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC.
Gene References into Functions
  1. The current results suggested that genetic variants at TEP1 SNPs rs1760893 and rs1713423 may be associated significantly with increased risk of stomach cancer. PMID: 27305982
  2. TEP1 Polymorphisms are not associated with Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B Virus Infection. PMID: 27221889
  3. These data suggest that genetic variations in the TEP1 gene may be biomarkers for risk of PCa and BCR after RP. PMID: 26238235
  4. 8 common SNPs in telomerase reverse transcriptase (TERT) and telomerase-associated protein 1 (TEP1) were genotyped. PMID: 24269974
  5. the protein levels of MVP, TEP1 and vPARP are actually increased in the highergrade tumors suggesting existence of post-transcriptional regulation of vault component production. PMID: 23739867
  6. TP1 expression did not change after cisplatin exposure for 72 hours. PMID: 11942411
  7. TEP1, hTR, hsp90, p23, and dyskerin remained at high and unchanged levels throughout up- or down regulation of telomerase activity. PMID: 12135483
  8. expression of telomerase activity and its subunit level in pancreatic carcinoma significantly correlate with the clinical stage of pancreatic carcinoma PMID: 12918126
  9. Telomerase activity and hTERT, TP-1 mRNA expression are up-regulated in esophageal squamous cell carcinoma PMID: 14606063
  10. The epithelial expression of TP-1 is elevated in mildly active UC. PMID: 18938767
  11. TEP1, TOPOIIalpha, and HSP90 interact directly with BLM in vitro and modulate its helicase activity on telomere-like DNA substrates but not on non-telomeric substrates. PMID: 19329795

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Subcellular Location
Nucleus. Chromosome, telomere.
Tissue Specificity
Database Links

HGNC: 11726

OMIM: 601686

KEGG: hsa:7011

STRING: 9606.ENSP00000262715

UniGene: Hs.508835

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