Pka-C1 Antibody

^{Rare Species}

Datasheet

Code	CSB-PA318954LA01DLU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster Pka-C1 Polyclonal antibody

Uniprot No.

P12370

Target Names

Pka-C1

Alternative Names

Pka-C1 antibody; CdkA antibody; DC0 antibody; CG4379 antibody; cAMP-dependent protein kinase catalytic subunit 1 antibody; PKA C antibody; EC 2.7.11.11 antibody; Protein kinase DC0 antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster

Immunogen

Recombinant Drosophila melanogaster cAMP-dependent protein kinase catalytic subunit 1 protein (2-353AA)

Immunogen Species

Drosophila melanogaster

Conjugate

Non-conjugated

The Pka-C1 Antibody (Product code: CSB-PA318954LA01DLU) is Non-conjugated. For Pka-C1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA318954LB01DLU	Pka-C1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA318954LC01DLU	Pka-C1 Antibody, FITC conjugated
Biotin	CSB-PA318954LD01DLU	Pka-C1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Serine/threonine-protein kinase involved in memory formation. Promotes long-term memory by phosphorylating meng and by regulating CrebB protein stability and activity. As part of ethanol response in the glia, mediates ethanol-induced structural remodeling of actin cytoskeleton and perineurial membrane topology when anchored to the membrane.

Gene References into Functions

Hedgehog signalling activation causes PKA to switch its substrates from Ci to Smo within the Hh signalling complex. PMID: 25289679
tightly controlled dose-dependent intra-neuronal PKA activity levels are critical in determining the dendritic arbor complexity, one of the possible ways being through the regulation of organelle distribution. PMID: 25017992
Alpha- NAC is a substrate of PKA following Parathyroid Hormone signaling. PMID: 24550008
that manipulations that increase cAMP/PKA signaling in adipokinetic hormone (AKH)-producing cells at the base of the neuroendocrine ring gland restore the dNf1 growth deficiency. PMID: 24278035
Acute expression of protein kinase A inhibitory peptide in aged animals is sufficient to reverse age-related memory impairment in wild-type animals. PMID: 21084612
Two-dimensional gel electrophoresis, (32)P labelling and immunodetection show that "in vitro" PKA phosphorylates the serine in the C-terminus of the NDUFS4 subunit in isolated bovine complex I. PMID: 20433953
Its signaling underlies age-related memory impairment.(review) PMID: 18646611
We found that decreased PKA activity in neurons rendered flies insensitive to the wake-promoting effects of octopamine. PMID: 18799671

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Protein Families

Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily

Tissue Specificity

More abundant in adult head than adult body.

Database Links

KEGG: dme:Dmel_CG4379

STRING: 7227.FBpp0079448

UniGene: Dm.2136

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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