RAB8B Antibody

Code CSB-PA019223GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
RAB8B
Alternative Names
5930437D16 antibody; D330025I23Rik antibody; FLJ38125 antibody; GTPase Rab8b antibody; RAB 8b protein antibody; RAB44 antibody; Rab8b antibody; RAB8B, member RAS oncogene family antibody; RAB8B_HUMAN antibody; Ras-related protein Rab-8B antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human RAB8B
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells.
Gene References into Functions
  1. Rab8A GTPase Ser(111) phosphorylation is not directly regulated by PINK1 in vitro and demonstrate in cells the time course of Ser(111) phosphorylation of Rab8A, 8B and 13 is markedly delayed compared to phosphorylation of Parkin at Ser(65). PMID: 26471730
Subcellular Location
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.
Protein Families
Small GTPase superfamily, Rab family
Database Links

HGNC: 30273

OMIM: 613532

KEGG: hsa:51762

STRING: 9606.ENSP00000312734

UniGene: Hs.389733

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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