RASL10A Antibody

Code CSB-PA006673
Size US$100
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  • Western Blot analysis of MOUSE-SPLEEN cells using RRP22 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
RASL10A
Alternative Names
RASL10A antibody; RRP22 antibody; Ras-like protein family member 10A antibody; Ras-like protein RRP22 antibody; Ras-related protein on chromosome 22 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the Internal region of Human RRP22.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Potent inhibitor of cellular proliferation.
Gene References into Functions
  1. RRP22 is a special neural tumor suppressor for human astrocytomas PMID: 21264544
  2. Both 5'-CpG island hypermethylation and histone modifications contribute to the frequent and prognostically unfavorable transcriptional downregulation of RRP22 in malignant gliomas. PMID: 21631628
  3. chromosome 22 have specific motor deficits in axial stability and graphomotor skills. PMID: 20646714
  4. RRP22 localizes to the nucleolus in a GTP-dependent manner and can serve as a potential tumor suppressor. PMID: 15833841
Subcellular Location
Cell membrane; Lipid-anchor; Cytoplasmic side. Nucleus, nucleolus. Note=May cycle in and out of the nucleolus in a GTP-dependent manner.
Protein Families
Small GTPase superfamily, Ras family
Tissue Specificity
Expression appears to be strictly limited to the central nervous system.
Database Links

HGNC: 16954

OMIM: 602220

KEGG: hsa:10633

STRING: 9606.ENSP00000216101

UniGene: Hs.73088

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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