RBAK Antibody

Code CSB-PA003952
Size US$119
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  • Western Blot analysis of HepG2 cells using RBAK Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
RBAK
Alternative Names
hRBaK antibody; Hypothetical protein RBAK antibody; RB associated KRAB zinc finger antibody; RB-associated KRAB repressor antibody; RB-associated KRAB zinc finger protein antibody; RBAK antibody; RBAK_HUMAN antibody; Zinc finger protein 769 antibody; ZNF 769 antibody; ZNF769 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of Human RBAK.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
May repress E2F-dependent transcription. May promote AR-dependent transcription.
Gene References into Functions
  1. Studies indicate that data on the regulatory functions of the KRAB-ZFP in embryonic development and tumorgenesis will benefit the understanding of biological roles of KRAB-ZFP in different physiological and pathological states. PMID: 20466629
  2. RBaK interacts with the androgen receptor and increases its transcriptional activity. PMID: 14664718
  3. study found no evidence of mutations in the coding sequence and splice sites of RBaK in association with familial hyperaldosteronism type II PMID: 17121540
  4. The role of RBaK, PMS2, and GNA12 in the inheritance of familial hyperaldosteronism type II were studied. PMID: 18307725
Subcellular Location
Nucleus.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Tissue Specificity
Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.
Database Links

HGNC: 17680

OMIM: 608191

KEGG: hsa:57786

STRING: 9606.ENSP00000275423

UniGene: Hs.396178

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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