RBM6 Antibody

Code CSB-PA006412
Size US$100
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Product Details

Uniprot No.
Target Names
RBM6
Alternative Names
3G2 antibody; 4930506F14Rik antibody; DEF 3 antibody; DEF3 antibody; DKFZp686B0877 antibody; FLJ36517 antibody; g16 antibody; HLC 11 antibody; KIAA4015 antibody; Lung cancer antigen NY LU 12 antibody; Lung cancer antigen NY-LU-12 antibody; Lung cancer protooncogene 11 antibody; mKIAA4015 antibody; NY LU 12 antibody; Protein G16 antibody; RBM6 antibody; RBM6/RBM5 fusion antibody; RBM6_HUMAN antibody; RGD1560367 antibody; RNA binding motif protein 6 antibody; RNA-binding motif protein 6 antibody; RNA-binding protein 6 antibody; RNA-binding protein DEF-3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of Human DEF-3.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Specifically binds poly(G) RNA homopolymers in vitro.
Gene References into Functions
  1. Antagonizes the effects of RBM5, RBM6, and RBM10 in cell colony formation. PMID: 24332178
  2. identified a novel fusion of the RNA binding motif 6 (RBM6) gene to CSF1R gene generated presumably by a t(3;5)(p21;q33) translocation that induced a myeloid proliferative disease with features of megakaryoblastic leukemia in a murine transplant model PMID: 17360941
  3. RBM6 mRNA experiences altered co-transcriptional gene regulation in certain cancers. RBM6-RBM5 transcription-induced chimerism might be a process that is linked to the tumour-associated increased transcriptional activity of the RBM6 gene PMID: 17908320
Subcellular Location
Nucleus.
Tissue Specificity
Ubiquitous in adults.
Database Links

HGNC: 9903

OMIM: 606886

KEGG: hsa:10180

STRING: 9606.ENSP00000266022

UniGene: Hs.696735

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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