REEP2 Antibody

Code CSB-PA019541GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
REEP2
Alternative Names
REEP2; C5orf19; SGC32445; Receptor expression-enhancing protein 2
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human REEP2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors.
Gene References into Functions
  1. Expression of the REEP1/REEP2 subfamily appears to be restricted to neuronal and neuronal-like exocytotic tissues, consistent with neuronally restricted symptoms of REEP1 genetic disorders. PMID: 24355597
  2. We have identified mutations in REEP2 in two families with relatively pure, early-onset hereditary spastic paraplegia, one with autosomal-dominant and the other with autosomal-recessive transmission. PMID: 24388663
  3. In mouse, Reep2 enhances sweet receptor function by a different mechanism than Reep1 uses to enhance olfactory receptor function. PMID: 20943918
Involvement in disease
Spastic paraplegia 72 (SPG72)
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
DP1 family
Tissue Specificity
Detected in brain, heart and skeletal muscle, and at low levels in placenta, kidney and pancreas. Expressed in circumvallate papillae.
Database Links

HGNC: 17975

OMIM: 609347

KEGG: hsa:51308

STRING: 9606.ENSP00000254901

UniGene: Hs.416090

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