RERE Antibody

Code CSB-PA030941
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA030941(RERE Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA030941(RERE Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
RERE
Alternative Names
1110033A15Rik antibody; AI414665 antibody; ARG antibody; arginine glutamic acid dipeptide (RE) repeats antibody; arginine glutamic acid dipeptide repeats antibody; Arginine glutamic acid dipeptide repeats protein antibody; Arginine-glutamic acid dipeptide repeats protein antibody; ARGININE-GLUTAMIC ACID REPEATS-ENCODING GENE antibody; ARP antibody; ATN1L antibody; Atr2 antibody; atrophin 1 like antibody; Atrophin 1 like protein antibody; Atrophin 1 related protein antibody; atrophin 2 antibody; atrophin related protein antibody; ATROPHIN-1-ASSOCIATED PROTEIN antibody; Atrophin-1-like protein antibody; Atrophin-1-related protein antibody; atrophin-2 antibody; ATROPHIN-RELATED PROTEIN antibody; AW742570 antibody; DNB1 antibody; FLJ38775 antibody; KIAA0458 antibody; mKIAA0458 antibody; NEDBEH antibody; OTTHUMP00000001701 antibody; Rere antibody; RERE_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide of Human RERE
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.
Gene References into Functions
  1. suggest that mutations in RERE cause a genetic syndrome and that haploinsufficiency of RERE might be sufficient to cause many of the phenotypes associated with proximal 1p36 deletions PMID: 27087320
  2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  3. Observational study of gene-disease association. (HuGE Navigator) PMID: 18597038
  4. The mouse ortholog of RERE is required for embryonic development PMID: 14645126
Involvement in disease
Neurodevelopmental disorder with or without anomalies of the brain, eye, or heart (NEDBEH)
Subcellular Location
Nucleus. Note=Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.
Tissue Specificity
Widely expressed. Expressed in tumor cell lines.
Database Links

HGNC: 9965

OMIM: 605226

KEGG: hsa:473

STRING: 9606.ENSP00000338629

UniGene: Hs.463041

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