RERE Antibody

Code CSB-PA011436
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA011436(RERE Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA011436(RERE Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
RERE
Alternative Names
1110033A15Rik antibody; AI414665 antibody; ARG antibody; arginine glutamic acid dipeptide (RE) repeats antibody; arginine glutamic acid dipeptide repeats antibody; Arginine glutamic acid dipeptide repeats protein antibody; Arginine-glutamic acid dipeptide repeats protein antibody; ARGININE-GLUTAMIC ACID REPEATS-ENCODING GENE antibody; ARP antibody; ATN1L antibody; Atr2 antibody; atrophin 1 like antibody; Atrophin 1 like protein antibody; Atrophin 1 related protein antibody; atrophin 2 antibody; atrophin related protein antibody; ATROPHIN-1-ASSOCIATED PROTEIN antibody; Atrophin-1-like protein antibody; Atrophin-1-related protein antibody; atrophin-2 antibody; ATROPHIN-RELATED PROTEIN antibody; AW742570 antibody; DNB1 antibody; FLJ38775 antibody; KIAA0458 antibody; mKIAA0458 antibody; NEDBEH antibody; OTTHUMP00000001701 antibody; Rere antibody; RERE_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide of Human RERE
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.
Gene References into Functions
  1. suggest that mutations in RERE cause a genetic syndrome and that haploinsufficiency of RERE might be sufficient to cause many of the phenotypes associated with proximal 1p36 deletions PMID: 27087320
  2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  3. Observational study of gene-disease association. (HuGE Navigator) PMID: 18597038
  4. The mouse ortholog of RERE is required for embryonic development PMID: 14645126
Involvement in disease
Neurodevelopmental disorder with or without anomalies of the brain, eye, or heart (NEDBEH)
Subcellular Location
Nucleus. Note=Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.
Tissue Specificity
Widely expressed. Expressed in tumor cell lines.
Database Links

HGNC: 9965

OMIM: 605226

KEGG: hsa:473

STRING: 9606.ENSP00000338629

UniGene: Hs.463041

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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