RGS9BP Antibody, FITC conjugated

Code CSB-PA765076LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RGS9BP Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
RGS9BP antibody; R9AP antibody; Regulator of G-protein signaling 9-binding protein antibody; RGS9-anchoring protein antibody
Raised in
Species Reactivity
Recombinant Human Regulator of G-protein signaling 9-binding protein (1-210AA)
Immunogen Species
Homo sapiens (Human)
Purification Method
Antigen Affinity Purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation.
Gene References into Functions
  1. Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and genetic testing. (HuGE Navigator) PMID: 19948975
  2. This is the first report describing a nonsense mutation in RGS9. PMID: 19818506
  3. five unrelated patients with recessive mutations in the genes encoding either RGS9 or R9AP who report difficulty adapting to sudden changes in luminance levels mediated by cones PMID: 14702087
  4. homozygous mutations in R9AP gene that encodes the photoreceptor GTPase accelerating protein and its anchor protein, respectively, have been identifird in patients with bradyopsia. PMID: 17698770
  5. As the light level is increased and the PDE6* concentration in the normal rises relative to that in the observer lacking RGS9-1, the temporal advantage of the latter is soon lost, leaving only the deficit due to delayed deactivation. PMID: 18318613

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Involvement in disease
Prolonged electroretinal response suppression (PERRS)
Subcellular Location
Membrane; Single-pass type IV membrane protein.
Protein Families
RGS7BP/RGS9BP family
Database Links

HGNC: 30304

OMIM: 607814

KEGG: hsa:388531

STRING: 9606.ENSP00000334134

UniGene: Hs.528491

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