RIC1 Antibody

Code CSB-PA671121LA01HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
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  • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA671121LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA671121LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) RIC1 Polyclonal antibody
Uniprot No. Q4ADV7
Target Names RIC1
Alternative Names Connexin-43-interacting protein of 150 kDa antibody; Kiaa1432 antibody; Protein RIC1 homolog antibody; RIC1_HUMAN antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human RAB6A-GEF complex partner protein 1 protein (951-1233AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Applications : Immunohistochemistry

Sample type: serum

Review: IHC staining showing AAV-Runx1 overexpression-inducedchanges in RIC1 expression in articular cartilage at 12 weeks after ACLT surgery.

By Anonymous

Target Background

Function
(From Uniprot)
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP, and may thereby be required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. Required for phosphorylation and localization of GJA1. Is a regulator of procollagen transport and secretion, and is required for correct cartilage morphogenesis and development of the craniofacial skeleton.
Gene References into Functions
  1. KIAA1432 is a novel gene activated by amplification in Small Cell Lung Cancers. PMID: 23716474
  2. These results suggest that the newly identified domain is essential for the proper phosphorylation and localization of Cx43, and CIP150 is a novel partner protein targeting this domain. PMID: 16112082
Subcellular Location Cytoplasm, cytosol. Membrane.
Protein Families RIC1 family
Tissue Specificity Present in kidney and various cell lines (at protein level). Widely expressed at low level.
Database Links

HGNC: 17686

OMIM: 610354

KEGG: hsa:57589

STRING: 9606.ENSP00000416696

UniGene: Hs.211520

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