RIC1 Antibody

Datasheet

Citations (1)

Code	CSB-PA671121LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA671121LA01HU at dilution of 1:100 Immunofluorescent analysis of HepG2 cells using CSB-PA671121LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
Citations
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RIC1 Polyclonal antibody

Uniprot No.

Q4ADV7

Target Names

RIC1

Alternative Names

Connexin-43-interacting protein of 150 kDa antibody; Kiaa1432 antibody; Protein RIC1 homolog antibody; RIC1_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human RAB6A-GEF complex partner protein 1 protein (951-1233AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The RIC1 Antibody (Product code: CSB-PA671121LA01HU) is Non-conjugated. For RIC1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA671121LB01HU	RIC1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA671121LC01HU	RIC1 Antibody, FITC conjugated
Biotin	CSB-PA671121LD01HU	RIC1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

Runx1 protects against the pathological progression of osteoarthritis C Zhou,Bone Research,2021

Customer Reviews and Q&A

■ Customer Reviews

Average Rating:

5.0 - 1 reviews

Submit a Review here

Applications : Immunohistochemistry

Sample type: serum

Review: IHC staining showing AAV-Runx1 overexpression-inducedchanges in RIC1 expression in articular cartilage at 12 weeks after ACLT surgery.

By Anonymous

Target Background

Function

The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP, and may thereby be required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. Required for phosphorylation and localization of GJA1. Is a regulator of procollagen transport and secretion, and is required for correct cartilage morphogenesis and development of the craniofacial skeleton.

Gene References into Functions

KIAA1432 is a novel gene activated by amplification in Small Cell Lung Cancers. PMID: 23716474
These results suggest that the newly identified domain is essential for the proper phosphorylation and localization of Cx43, and CIP150 is a novel partner protein targeting this domain. PMID: 16112082

Subcellular Location

Cytoplasm, cytosol. Membrane.

Protein Families

RIC1 family

Tissue Specificity

Present in kidney and various cell lines (at protein level). Widely expressed at low level.

Database Links

HGNC: 17686

OMIM: 610354

KEGG: hsa:57589

STRING: 9606.ENSP00000416696

UniGene: Hs.211520

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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