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RIC1 Antibody, FITC conjugated

Datasheet
Code CSB-PA671121LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RIC1 Polyclonal antibody
Uniprot No.
Q4ADV7
Target Names
RIC1
Alternative Names
Connexin-43-interacting protein of 150 kDa antibody; Kiaa1432 antibody; Protein RIC1 homolog antibody; RIC1_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human RAB6A-GEF complex partner protein 1 protein (951-1233AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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RIC1 Antibodies

RIC1 Proteins

Customer Reviews and Q&A

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Target Background

Function
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP, and may thereby be required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. Required for phosphorylation and localization of GJA1. Is a regulator of procollagen transport and secretion, and is required for correct cartilage morphogenesis and development of the craniofacial skeleton.
Gene References into Functions
  1. KIAA1432 is a novel gene activated by amplification in Small Cell Lung Cancers. PMID: 23716474
  2. These results suggest that the newly identified domain is essential for the proper phosphorylation and localization of Cx43, and CIP150 is a novel partner protein targeting this domain. PMID: 16112082
Subcellular Location
Cytoplasm, cytosol. Membrane.
Protein Families
RIC1 family
Tissue Specificity
Present in kidney and various cell lines (at protein level). Widely expressed at low level.
Database Links

HGNC: 17686

OMIM: 610354

KEGG: hsa:57589

STRING: 9606.ENSP00000416696

UniGene: Hs.211520

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