RIN3 Antibody, HRP conjugated

1. RIN3 may be involved in endolysosomal transport-a process known to be important to development of early onset AD. PMID: 28738127
2. RIN3 may contribute to Paget's disease of bone susceptibility by affecting osteoclast function. PMID: 25701875
3. discovered novel interaction candidates for CD2AP and characterized subtle yet significant differences in the recognition preferences of its three SH3 domains for c-CBL, ALIX, and RIN3 PMID: 26296892
4. The study reports a novel association between a variant within RIN3 and lower limb-bone mineral density and note its previous association with risk of Paget's disease. PMID: 24945404
5. RIN3 is a negative regulator of mast cell responses to SCF PMID: 23185384
6. RIN3 specifically acts as a GEF for Rab31. PMID: 21586568
7. RIN3 biochemically characterized as the stimulator and stabilizer for GTP-Rab5 plays an important role in the transport pathway from plasma membrane to early endosomes PMID: 12972505
8. Tyrosine-phosphorylation signals are involved in the RIN3 activation and translocation to early endocytic vesicles. PMID: 18486601

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HGNC: 18751

OMIM: 610223

KEGG: hsa:79890

STRING: 9606.ENSP00000216487

UniGene: Hs.326822