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RNF103 Antibody, HRP conjugated

Datasheet
Code CSB-PA019815LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RNF103 Polyclonal antibody
Uniprot No.
O00237
Target Names
RNF103
Alternative Names
RNF103; ZFP103; E3 ubiquitin-protein ligase RNF103; KF-1; hKF-1; RING finger protein 103; RING-type E3 ubiquitin transferase RNF103; Zinc finger protein 103 homolog; Zfp-103
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human E3 ubiquitin-protein ligase RNF103 protein (432-685AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway.
Gene References into Functions
  1. Analysis reveals that the main determinants of selectivity between ubiquitin ligases RNF103 and E2 ubiquitin-conjugating enzymes resides on ring domains, rather than on the E2s. PMID: 18615712
  2. Kf-1 is an ER ubiquitin ligase involved in the endoplasmic reticulum-associated degradation pathway. PMID: 18675248
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity
Highly expressed in the normal cerebellum but not in the cerebral cortex.
Database Links

HGNC: 12859

OMIM: 602507

KEGG: hsa:7844

STRING: 9606.ENSP00000237455

UniGene: Hs.469199

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