RNF144A Antibody

Code CSB-PA004357
Size US$100
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  • Western Blot analysis of COLO205 cells using UBCE7IP4 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
RNF144A
Alternative Names
RNF144A; KIAA0161; RNF144; UBCE7IP4; E3 ubiquitin-protein ligase RNF144A; RING finger protein 144A; UbcM4-interacting protein 4; Ubiquitin-conjugating enzyme 7-interacting protein 4
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the Internal region of Human UBCE7IP4.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC.
Gene References into Functions
  1. both proper membrane localization and self-association are important for RNF144A function. PMID: 26216882
  2. The regulation of DNA-PKcs by RNF144A is important for proper apoptotic response during DNA damage, suggesting a tumor suppressor function for RNF144A. PMID: 24979766
  3. Clinical trial and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20195266
  4. Functional analysis of the mouse counterpart. PMID: 10431818
Subcellular Location
Cell membrane; Single-pass membrane protein. Cytoplasmic vesicle membrane.
Protein Families
RBR family, RNF144 subfamily
Database Links

HGNC: 20457

KEGG: hsa:9781

STRING: 9606.ENSP00000321330

UniGene: Hs.22146

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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