RPIA Antibody,FITC conjugated

Code CSB-PA020104LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RPIA Polyclonal antibody
Uniprot No.
Target Names
RPIA
Alternative Names
EC 5.3.1.6 antibody; MGC103524 antibody; Phosphoriboisomerase A antibody; Phosphoriboisomerase antibody; Ribose 5 phosphate isomerase antibody; ribose 5-phosphate epimerase antibody; ribose 5-phosphate isomerase A antibody; Ribose-5-phosphate isomerase antibody; RPI antibody; rpiA antibody; RPIA_HUMAN antibody; zgc:103524 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ribose-5-phosphate isomerase protein (1-311AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Antigen Affinity purified & Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. The results are consistent with a model in which RPIA suppresses autophagy and LC3 processing by modulation of redox signaling. PMID: 27328773
  2. CRC cells that overexpressed miR124 or with knockdown of RPIA or PRPS1 had reduced DNA synthesis and proliferation, whereas cells incubated with an inhibitor of miR124 had significantly increased DNA synthesis and proliferation and formed more colonies. PMID: 26248089
  3. In this work, through an in silico comparative analysis between the genomes of Leishmania major and Homo sapiens, the enzyme ribose 5-phosphate isomerase (R5PI) was indicated as a promising molecular target. PMID: 25528729
  4. Study provides new insight into the molecular mechanisms by which RPIA overexpression can induce oncogenesis in hepatocellular carcinoma. PMID: 25429733
  5. RPI is the second known inborn error in the reversible phase of the pentose-phosphate-pathway, confirming that defects in pentose and polyol metabolism constitute a new area of inborn metabolic disorders PMID: 14988808

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Involvement in disease
Ribose 5-phosphate isomerase deficiency (RPID)
Protein Families
Ribose 5-phosphate isomerase family
Database Links

HGNC: 10297

OMIM: 180430

KEGG: hsa:22934

STRING: 9606.ENSP00000283646

UniGene: Hs.469264

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