RPS23 Antibody, Biotin conjugated

Code CSB-PA020400LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RPS23 Polyclonal antibody
Uniprot No.
Target Names
RPS23
Alternative Names
40S ribosomal protein S23 antibody; FLJ35016 antibody; Homolog of yeast ribosomal protein S28 antibody; Ribosomal protein S23 antibody; RPS 23 antibody; RPS23 antibody; RS23_HUMAN antibody; S23 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human 40S ribosomal protein S23 protein (2-143AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays an important role in translational accuracy.
Gene References into Functions
  1. A missense mutation is reported in two unrelated individuals with microcephaly, hearing loss, and overlapping dysmorphic features. PMID: 28257692
  2. Report dysregulated expression of RPS23 in disc degeneration. PMID: 25893343
  3. Rps23p hydroxylation can either increase or decrease translational accuracy in a stop codon context-dependent manner. PMID: 24550462
Involvement in disease
Brachycephaly, trichomegaly, and developmental delay (BTDD)
Subcellular Location
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum.
Protein Families
Universal ribosomal protein uS12 family
Database Links

HGNC: 10410

OMIM: 603683

KEGG: hsa:6228

STRING: 9606.ENSP00000296674

UniGene: Hs.527193

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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