RPS23 Antibody

Datasheet

Code	CSB-PA020400LA01HU
Size	US$166
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Image	Immunofluorescence staining of Hela cells with CSB-PA020400LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RPS23 Polyclonal antibody

Uniprot No.

P62266

Target Names

RPS23

Alternative Names

40S ribosomal protein S23 antibody; FLJ35016 antibody; Homolog of yeast ribosomal protein S28 antibody; Ribosomal protein S23 antibody; RPS 23 antibody; RPS23 antibody; RS23_HUMAN antibody; S23 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human 40S ribosomal protein S23 protein (2-143AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The RPS23 Antibody (Product code: CSB-PA020400LA01HU) is Non-conjugated. For RPS23 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA020400LB01HU	RPS23 Antibody, HRP conjugated	ELISA
FITC	CSB-PA020400LC01HU	RPS23 Antibody, FITC conjugated
Biotin	CSB-PA020400LD01HU	RPS23 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays an important role in translational accuracy.

Gene References into Functions

A missense mutation is reported in two unrelated individuals with microcephaly, hearing loss, and overlapping dysmorphic features. PMID: 28257692
Report dysregulated expression of RPS23 in disc degeneration. PMID: 25893343
Rps23p hydroxylation can either increase or decrease translational accuracy in a stop codon context-dependent manner. PMID: 24550462

Involvement in disease

Brachycephaly, trichomegaly, and developmental delay (BTDD)

Subcellular Location

Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum.

Protein Families

Universal ribosomal protein uS12 family

Database Links

HGNC: 10410

OMIM: 603683

KEGG: hsa:6228

STRING: 9606.ENSP00000296674

UniGene: Hs.527193

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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