RTFDC1 Antibody

Code CSB-PA003714GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
RTFDC1
Alternative Names
RTF2 antibody; C20orf43 antibody; RTFDC1 antibody; AD-007 antibody; CDA05 antibody; HSPC164 antibody; HSPC169 antibody; Replication termination factor 2 antibody; RTF2 antibody; Replication termination factor 2 domain-containing protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human C20orf43
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Replication termination factor which is a component of the elongating replisome. Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion. Interacts with nascent DNA.
Gene References into Functions
  1. The results establish that RTF2 removal is a key determinant for the ability of cells to manage replication stress and maintain genome integrity. PMID: 29290612
Subcellular Location
Chromosome.
Protein Families
Rtf2 family
Database Links

HGNC: 15890

KEGG: hsa:51507

STRING: 9606.ENSP00000023939

UniGene: Hs.517134

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