RTKN2 Antibody

Code CSB-PA810311LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA810311LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA810311LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RTKN2 Polyclonal antibody
Uniprot No.
Target Names
RTKN2
Alternative Names
RTKN2 antibody; PLEKHK1Rhotekin-2 antibody; Pleckstrin homology domain-containing family K member 1 antibody; PH domain-containing family K member 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Rhotekin-2 protein (1-163AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The RTKN2 Antibody (Product code: CSB-PA810311LA01HU) is Non-conjugated. For RTKN2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA810311LB01HU RTKN2 Antibody, HRP conjugated ELISA
FITC CSB-PA810311LC01HU RTKN2 Antibody, FITC conjugated
Biotin CSB-PA810311LD01HU RTKN2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play an important role in lymphopoiesis.
Gene References into Functions
  1. RTKN2 was upregulated in human bladder cancer tissues and cell lines. Silencing of RTKN2 inhibited proliferation and invasion, and induced cell apoptosis. In addition, knockdown of RTKN2 arrested the cell cycle at the G1 phase via inhibition of the expression of cell cycle-associated proteins. PMID: 27082503
  2. RTKN2 was overexpressed in HCC tissues. RTKN2 served an important role in tumorigenesis and metastasis of HCC. PMID: 27081789
  3. miR-1246 promotes UVB-induced apoptosis by downregulating RTKN2 expression and that UVB-upregulated miR-1246 released RTKN2-dependent resistance to UVB-induced apoptosis by targeting RTKN2 post-transcriptionally in keratinocyte cells. PMID: 24880483
  4. we identified two gene loci associated with rheumatoid arthritis susceptibility- NFKBIE and RTKN2 PMID: 23028356
  5. Cloning and characterization of gene expression of rhotekin-2. PMID: 15504364

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Tissue Specificity
Expressed in lymphocytes, CD4 positive T-cells and bone marrow-derived cells. Also expressed in lung, colon, thymus and brain.
Database Links

HGNC: 19364

KEGG: hsa:219790

UniGene: Hs.58559

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