RTN4RL1 Antibody

Datasheet

Code	CSB-PA803121LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA803121LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA803121LA01HU at dilution of 1:100 Immunofluorescent analysis of A549 cells using CSB-PA803121LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RTN4RL1 Polyclonal antibody

Uniprot No.

Q86UN2

Target Names

RTN4RL1

Alternative Names

DKFZp547J144 antibody; NgR 3 antibody; NgR3 antibody; NGRH 2 antibody; NGRH2 antibody; NGRL2 antibody; Nogo 66 receptor homolog 2 antibody; Nogo 66 receptor related protein 3 antibody; Nogo receptor like 2 antibody; Nogo receptor-like 2 antibody; Nogo-66 receptor homolog 2 antibody; Nogo-66 receptor-related protein 3 antibody; R4RL1_HUMAN antibody; Reticulon 4 receptor like 1 antibody; Reticulon-4 receptor-like 1 antibody; RTN4RL1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Reticulon-4 receptor-like 1 protein (201-420AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The RTN4RL1 Antibody (Product code: CSB-PA803121LA01HU) is Non-conjugated. For RTN4RL1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA803121LB01HU	RTN4RL1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA803121LC01HU	RTN4RL1 Antibody, FITC conjugated
Biotin	CSB-PA803121LD01HU	RTN4RL1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Cell surface receptor. Plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG. Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans. Binds heparin. Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton.

Gene References into Functions

Duplication of 10q22.3-q23.3 encompassing NGR3 gene is associated with congenital heart disease, microcephaly, and mild intellectual disability PMID: 26383923
predominantly expressed in the neurons of the embryonic and adult nervous systems PMID: 14664809

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft. Perikaryon. Cell projection.

Protein Families

Nogo receptor family

Tissue Specificity

Predominantly expressed in brain. Expressed at lower levels in kidney, lung, mammary gland, placenta, salivary gland, skeletal muscle and spleen.

Database Links

HGNC: 21329

OMIM: 610461

KEGG: hsa:146760

STRING: 9606.ENSP00000330631

UniGene: Hs.22917

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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