RUFY3 Antibody, FITC conjugated

Code CSB-PA765974LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RUFY3 Polyclonal antibody
Uniprot No.
Target Names
RUFY3
Alternative Names
Protein RUFY3 antibody; rap2 interacting protein x antibody; Rap2 interacting protein x isoform 2 antibody; Rap2-interacting protein x antibody; RIPx antibody; Rpipx antibody; Rufy3 antibody; RUFY3_HUMAN antibody; RUN and FYVE domain containing 3 antibody; Singar antibody; Singar1 antibody; Single axon regulated protein antibody; single axon related 1 antibody; Single axon-regulated protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein RUFY3 protein (243-352AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in the generation of neuronal polarity formation and axon growth. Implicated in the formation of a single axon by developing neurons. May inhibit the formation of additional axons by inhibition of PI3K in minor neuronal processes. Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery. Plays a role in cytoskeletal organization by regulating the subcellular localization of FSCN1 and DBN1 at axonal growth cones. Promotes gastric cancer cell migration and invasion in a PAK1-dependent manner.
Gene References into Functions
  1. these findings provide important evidence that PAK1 can positively regulate RUFY3 expression, which contribute to the metastatic potential of gastric cancer cells PMID: 25766321
  2. Rab5(Q79L) interacts with the carboxyl terminus of RUFY3 PMID: 20376209
Subcellular Location
Cytoplasm. Endomembrane system. Cell projection, invadopodium. Perikaryon. Cell projection. Cell projection, growth cone. Cell projection, filopodium. Cell projection, lamellipodium.
Tissue Specificity
Overexpressed in gastric cancer cells and tissues (at protein level).
Database Links

HGNC: 30285

OMIM: 611194

KEGG: hsa:22902

STRING: 9606.ENSP00000370394

UniGene: Hs.740904

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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