MINPP1 Antibody

Datasheet

Code	CSB-PA891977EA01HU
Size	US$166
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Image	Western blot All lanes: MINPP1 antibody at 14μg/ml Lane 1: Jurkat whole cell lysate Lane 2: U251 whole cell lysate Lane 3: K562 whole cell lysate Lane 4: Hela whole cell lysate Lane 5: HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 56, 35, 32, 34 kDa Observed band size: 56 kDa Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA891977EA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MINPP1 Polyclonal antibody

Uniprot No.

Q9UNW1

Target Names

MINPP1

Alternative Names

3 antibody; 4 antibody; 5)-tetrakisphosphate 3-phosphatase antibody; 5)P(4) 3-phosphatase antibody; DKFZp564L2016 antibody; HIPER1 antibody; Inositol (1 antibody; inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase antibody; Ins(1 antibody; ins(1,3,4,5)P(4) 3-phosphatase antibody; MINP1_HUMAN antibody; Minpp1 antibody; MINPP2 antibody; MIPP antibody; Multiple inositol polyphosphate histidine phosphatase, 1 antibody; Multiple inositol polyphosphate phosphatase 1 antibody; multiple inositol polyphosphate phosphatase 2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Multiple inositol polyphosphate phosphatase 1 protein (31-487AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The MINPP1 Antibody (Product code: CSB-PA891977EA01HU) is Non-conjugated. For MINPP1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA891977EB01HU	MINPP1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA891977EC01HU	MINPP1 Antibody, FITC conjugated
Biotin	CSB-PA891977ED01HU	MINPP1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy.

Gene References into Functions

Minpp1 exhibits characteristics of a stress responsive molecule during Endoplasmic reticulum stress-induced apoptosis PMID: 27038811
By RNA knockdown, we identified secreted and lysosome targeted MINPP1 (multiple inositol-polyphosphate phosphatase 1), the mammalian 3-phytase, to be essentially involved both in extracellular and in lysosomal InsP6 dephosphorylation PMID: 23186306

Involvement in disease

Thyroid cancer, non-medullary, 2 (NMTC2)

Subcellular Location

Endoplasmic reticulum lumen.

Protein Families

Histidine acid phosphatase family, MINPP1 subfamily

Tissue Specificity

Widely expressed with highest levels in kidney, liver and placenta.

Database Links

HGNC: 7102

OMIM: 188470

KEGG: hsa:9562

STRING: 9606.ENSP00000361064

UniGene: Hs.121260

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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