DIMT1 Antibody

Code CSB-PA892161LA01HU
Size US$166
Order now
Image
  • Western blot
    All lanes: DIMT1 antibody at 2μg/ml + Mouse thymus tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 35 kDa
    Observed band size: 35 kDa

  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA892161LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA892161LA01HU at dilution of 1:100

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DIMT1 Polyclonal antibody
Uniprot No.
Target Names
DIMT1
Alternative Names
18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase antibody; 18S rRNA dimethylase antibody; DIM1 antibody; DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) antibody; DIM1 dimethyladenosine transferase 1 homolog antibody; DIM1 dimethyladenosine transferase 1 like antibody; DIM1 dimethyladenosine transferase 1-like antibody; Dimethyladenosine transferase antibody; DIMT1 antibody; DIMT1_HUMAN antibody; DIMT1L antibody; HSA9761 antibody; HUSSY5 antibody; N''-adenosyl(rRNA) dimethyltransferase antibody; Probable 18S rRNA (adenine(1779) N(6)/adenine(1780) N(6)) dimethyltransferase antibody; Probable 18S rRNA dimethylase antibody; Probable dimethyladenosine transferase antibody; Probable S adenosylmethionine 6 N',N' adenosyl(rRNA) dimethyltransferase antibody; S adenosylmethionine 6 N',N' adenosyl(rRNA) dimethyltransferase antibody; S-adenosylmethionine-6-N'' antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Probable dimethyladenosine transferase protein (1-313AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The DIMT1 Antibody (Product code: CSB-PA892161LA01HU) is Non-conjugated. For DIMT1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA892161LB01HU DIMT1 Antibody, HRP conjugated ELISA
FITC CSB-PA892161LC01HU DIMT1 Antibody, FITC conjugated
Biotin CSB-PA892161LD01HU DIMT1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity.
Gene References into Functions
  1. DIMT1 is overexpressed in gastric carcinoma and is significantly correlated with poor prognosis. PMID: 28601661
  2. Studies show that miroRNA miR-210 acts as a tumor suppressor in hypoxic conditions by downregulating the 18S rRNA base methyltransferase (DIMT1)-interferon regulatory factor 4 (IRF4) axis. PMID: 28164410
  3. DIMT1L and WBSCR22-TRMT112 are required for distinct pre-rRNA processing reactions leading to synthesis of 18S rRNA. Ribosome biogenesis requires the presence of the modification enzyme rather than its RNA-modifying catalytic activity. PMID: 25851604
  4. Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection by activating STMN1 and DIMT1. PMID: 25187177
Subcellular Location
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein Families
Class I-like SAM-binding methyltransferase superfamily, rRNA adenine N(6)-methyltransferase family
Database Links

HGNC: 30217

OMIM: 612499

KEGG: hsa:27292

STRING: 9606.ENSP00000199320

UniGene: Hs.731665

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*