SAP5 Antibody

Code CSB-PA337319XA01CZD
Size US$166
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  • Western Blot
    Positive WB detected in: recombinant protein
    All lanes:SAP5 Antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/20000 dilution
    Predicted band size: 44.1 kDa
    Observed band size: 44 kDa
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Product Details

Full Product Name
Rabbit anti-Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) SAP5 Polyclonal antibody
Uniprot No.
Target Names
SAP5
Alternative Names
Candidapepsin-5 (EC 3.4.23.24) (ACP 5) (Aspartate protease 5) (Secreted aspartic protease 5), SAP5
Raised in
Rabbit
Species Reactivity
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Immunogen
Recombinant Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) SAP5 protein (77-418aa)
Immunogen Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Secreted aspartic peptidases (SAPs) are a group of ten acidic hydrolases considered as key virulence factors. These enzymes supply the fungus with nutrient amino acids as well as are able to degrade the selected host's proteins involved in the immune defense. During infection, plays an important role in penetration into deeper tissues and interaction with host defense. Moreover, acts toward human hemoglobin though limited proteolysis to generate a variety of antimicrobial hemocidins, enabling to compete with the other microorganisms of the same physiological niche using the microbicidal peptides generated from the host protein.
Gene References into Functions
  1. expression of SAP5 was significantly down-regulated both in yeast treated with 500 and 1000 nM of siRNA PMID: 24658980
  2. Sap5, which is coproduced in the hyphal form, were clustered as the same group, indicating that they may target similar host proteins. PMID: 21646240
Subcellular Location
Secreted.
Protein Families
Peptidase A1 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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