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SBNO2 Antibody, Biotin conjugated

Datasheet
Code CSB-PA896873LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SBNO2 Polyclonal antibody
Uniprot No.
Q9Y2G9
Target Names
SBNO2
Alternative Names
SBNO2 antibody; KIAA0963Protein strawberry notch homolog 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Related Products

SBNO2 Antibodies

SBNO2 Proteins

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Target Background

Function
Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis; required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation. Involved in the transcriptional corepression of NF-kappaB in macrophages. Plays a role as a regulator in the proinflammatory cascade.
Gene References into Functions
  1. The SBNO2 is component of the pathways that contribute to the downstream anti-inflammatory effects of IL-10. PMID: 18025162
Protein Families
SBNO family
Tissue Specificity
Detected in macrophages. IL10 regulates expression in a STAT3-dependent way.
Database Links

HGNC: 29158

OMIM: 615729

KEGG: hsa:22904

STRING: 9606.ENSP00000354733

UniGene: Hs.408708

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