SBNO2 Antibody

Datasheet

Code	CSB-PA896873LA01HU
Size	US$166
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Image	Immunofluorescent analysis of HepG2 cells using CSB-PA896873LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SBNO2 Polyclonal antibody

Uniprot No.

Q9Y2G9

Target Names

SBNO2

Alternative Names

SBNO2 antibody; KIAA0963Protein strawberry notch homolog 2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SBNO2 Antibody (Product code: CSB-PA896873LA01HU) is Non-conjugated. For SBNO2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA896873LB01HU	SBNO2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA896873LC01HU	SBNO2 Antibody, FITC conjugated
Biotin	CSB-PA896873LD01HU	SBNO2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:20-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis; required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation. Involved in the transcriptional corepression of NF-kappaB in macrophages. Plays a role as a regulator in the proinflammatory cascade.

Gene References into Functions

The SBNO2 is component of the pathways that contribute to the downstream anti-inflammatory effects of IL-10. PMID: 18025162

Protein Families

SBNO family

Tissue Specificity

Detected in macrophages. IL10 regulates expression in a STAT3-dependent way.

Database Links

HGNC: 29158

OMIM: 615729

KEGG: hsa:22904

STRING: 9606.ENSP00000354733

UniGene: Hs.408708

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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