SCGB2A1 Antibody

1. The expression of HOXB13, IL17BR, and mammaglobin 1 in sentinel lymph nodes predict the outcome of primary breast cancer patients. PMID: 29729704
2. novel marker GATA3 stains a significantly higher proportion of both primary and metastatic breast carcinomas than GCDFP15 or mammaglobin with stronger and more diffuse staining, helpful in cases with small tissue samples PMID: 25906123
3. The commonly used breast carcinoma biomarkers vary in their prognostic implications. GCDFP-15 independently indicated a favourable prognosis. GATA-3 and MGB were not associated with outcome. PMID: 25425335
4. Results indicate that the quantitative analysis of h-MAM mRNA is a useful tool for detecting CTCs in breast cancer patients. PMID: 24706379
5. Results indicated that SCGB2A1 represented a novel, prognostic factor for colorectal cancer, and its expression correlated with chemoresistance, radioresistance and cancer cell stemness. PMID: 24585249
6. The data indicate that MGB1, MGB2 and LIPB mRNAs are expressed at low levels in human tissues but basal expression is upregulated in ovarian cancer. PMID: 24603286
7. SCGB2A1 is a top differentially expressed gene in all major histological types of ovarian cancers. PMID: 23807163
8. MGB has the highest expression in HER2-overexpressing breast cancers and may be a potentially useful marker for this subtype. PMID: 23332923
9. Data show that plasma mammaglobin mRNA alone or in combination with CA15.3 (CD227) may be used as a valuable noninvasive approach for the diagnosis and the detection of metastasis in breast cancer at the time of diagnosis. PMID: 20306663
10. The mammaglobin/lipophilin B complex is a promising diagnostic marker for breast cancer. PMID: 12022875
11. MGB2 markers may be useful for identifying micrometastases in sentinel lymph nodes of breast cancer patients. PMID: 15151203
12. SCGB 2A1 represents a new class of androgen target genes that are purely under indirect AR control mediated by DNA-bound Sp factors. PMID: 16020486
13. Results indicate that mammaglobin, as measured by the ELISA, holds significant promise for breast cancer screening with the realistic potential to impact management of this disease. PMID: 16166429
14. MGB-2 is highly expressed in endometrioid endometrial cancer [EEC], particularly in well- and moderately differentiated tumors, and may represent a novel molecular marker for EEC PMID: 18021217
15. Expression levels of mammaglobins A and B in nasal polyps are not different between patients with and without AR PMID: 18416968
16. MGB-2 expression characterizes less aggressive forms of EOC and is correlated with a favorable outcome PMID: 19635143

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HGNC: 7051

OMIM: 604398

KEGG: hsa:4246

STRING: 9606.ENSP00000244930

UniGene: Hs.97644