SCIMP Antibody, FITC conjugated

Datasheet
Code CSB-PA754405LC01HU
Size US$299
Uniprot No. Q6UWF3
Protocols ELISA Protocol
Immunogen Recombinant Human SLP adapter and CSK-interacting membrane protein (59-145AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Lipid tetraspanin-associated transmembrane adapter/mediator involved in major histocompatibility complex (MHC) class II signaling transduction. Required in generating the calcium response and enhancing ERK activity upon MHC-II stimulation.
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias SLP adapter and CSK-interacting membrane protein (SLP65/SLP76, Csk-interacting membrane protein), SCIMP, C17orf87
Immunogen Species Homo sapiens (Human)
Research Area Immunology
Target Names SCIMP
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Lipid tetraspanin-associated transmembrane adapter/mediator involved in major histocompatibility complex (MHC) class II signaling transduction. Required in generating the calcium response and enhancing ERK activity upon MHC-II stimulation.
Subcellular Location Membrane, Single-pass membrane protein, Membrane, Lipid-anchor
Tissue Specificity Expressed in antigen-presenting cells, like peripheral blood leukocytes and monocyte-derived dendritic cells (MDDC) (at protein level). Highly expressed in lymph nodes and spleen. Expressed in antigen-presenting cells. Faintly expressed in the majority of
Database Links

HGNC: 33504

OMIM: 614406

KEGG: hsa:388325

STRING: 9606.ENSP00000461269

UniGene: Hs.462080

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