SCLT1 Antibody

Code CSB-PA020826GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SCLT1
Alternative Names
SCLT1 antibody; SAP1 antibody; Sodium channel and clathrin linker 1 antibody; Sodium channel-associated protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human SCLT1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization.
Gene References into Functions
  1. study identified 2 cases with a severe ciliopathy phenotype consistent with oro-facio-digital syndrome type IX; the autozygome of each index harbored a single truncating variant and the affected genes (SCLT1 and TBC1D32/C6orf170) have roles in centrosomal biology and ciliogenesis; findings suggest a role of SCLT1 and TBC1D32 in ciliopathy pathogenesis PMID: 24285566
  2. Functional study in rat suggests that CAP-1A links clathrin and a sodium channel. PMID: 15797711
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane.
Database Links

HGNC: 26406

OMIM: 611399

KEGG: hsa:132320

STRING: 9606.ENSP00000281142

UniGene: Hs.654690

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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