SCLY Antibody

Code CSB-PA020827LA01HU
Size US$166
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Image
  • IHC image of CSB-PA020827LA01HU diluted at 1:700 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SCLY Polyclonal antibody
Uniprot No.
Target Names
SCLY
Alternative Names
hSCL antibody; Putative selenocysteine lyase antibody; SCL antibody; scly antibody; SCLY_HUMAN antibody; Selenocysteine lyase antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Selenocysteine lyase protein (3-138AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SCLY Antibody (Product code: CSB-PA020827LA01HU) is Non-conjugated. For SCLY Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA020827LB01HU SCLY Antibody, HRP conjugated ELISA
FITC CSB-PA020827LC01HU SCLY Antibody, FITC conjugated
Biotin CSB-PA020827LD01HU SCLY Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:500-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium.
Gene References into Functions
  1. the X-ray crystal structure of human selenocysteine lyase and the key residue that provides the selenocysteine specificity PMID: 22295093
  2. A reaction mechanism whereby the Selenocysteine over Cysteine specificity is achieved using a combination of chemical and physico-mechanical control mechanisms. PMID: 22291978
  3. Results confirm that HCV core protein is associated with specific changes in mRNA expression, including the gene for selenocysteine lyase, which may be involved in the pathophysiology of hepatocellular carcinoma. PMID: 16925092
  4. PMID:10692412 concerns mostly mouse selenocysteine lyase, however, refers to the sequence of the N-terminal region of putative human protein. PMID: 10692412
Subcellular Location
Cytoplasm, cytosol.
Protein Families
Class-V pyridoxal-phosphate-dependent aminotransferase family
Database Links

HGNC: 18161

OMIM: 611056

KEGG: hsa:51540

STRING: 9606.ENSP00000254663

UniGene: Hs.731909

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