SEC23IP Antibody, FITC conjugated

Datasheet

Code	CSB-PA896767LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SEC23IP Polyclonal antibody

Uniprot No.

Q9Y6Y8

Target Names

SEC23IP

Alternative Names

MSTP053 antibody; p125 antibody; P125A antibody; Phospholipase antibody; S23IP_HUMAN antibody; Sec23 interacting protein p125 antibody; SEC23-interacting protein antibody; SEC23IP antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human SEC23-interacting protein (779-989AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P).

Gene References into Functions

A basic cluster and a hydrophobic interface in the DDHD and SAM domains, respectively, are required for p125A-mediated functional endoplasmic reticulum exit site assembly. PMID: 24522181
Xenopus sec23ip is required for normal neural crest cell development, suggesting a role for the human ortholog in Waardenburg syndrome neural crest defects. PMID: 20308572
The results suggest that p125A is part of the Sec13/Sec31A subcomplex and facilitates ER export in mammalian cells. PMID: 20679433
p125 is a mammalian-specific component of ER exit sites and participates in the organization of this compartment PMID: 15623529

Subcellular Location

Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum.

Protein Families

PA-PLA1 family

Tissue Specificity

Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle.

Database Links

HGNC: 17018

OMIM: 617852

KEGG: hsa:11196

STRING: 9606.ENSP00000358071

UniGene: Hs.435004

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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