SEC23IP Antibody

Code CSB-PA896767LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Hela whole cell lysate
    All lanes: SEC23IP antibody at 2.7µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 112, 103 kDa
    Observed band size: 112 kDa

  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA896767LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA896767LA01HU at dilution of 1:100

  • Immunofluorescent analysis of Hela cells using CSB-PA896767LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SEC23IP Polyclonal antibody
Uniprot No.
Target Names
SEC23IP
Alternative Names
MSTP053 antibody; p125 antibody; P125A antibody; Phospholipase antibody; S23IP_HUMAN antibody; Sec23 interacting protein p125 antibody; SEC23-interacting protein antibody; SEC23IP antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human SEC23-interacting protein (779-989AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SEC23IP Antibody (Product code: CSB-PA896767LA01HU) is Non-conjugated. For SEC23IP Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA896767LB01HU SEC23IP Antibody, HRP conjugated ELISA
FITC CSB-PA896767LC01HU SEC23IP Antibody, FITC conjugated
Biotin CSB-PA896767LD01HU SEC23IP Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P).
Gene References into Functions
  1. A basic cluster and a hydrophobic interface in the DDHD and SAM domains, respectively, are required for p125A-mediated functional endoplasmic reticulum exit site assembly. PMID: 24522181
  2. Xenopus sec23ip is required for normal neural crest cell development, suggesting a role for the human ortholog in Waardenburg syndrome neural crest defects. PMID: 20308572
  3. The results suggest that p125A is part of the Sec13/Sec31A subcomplex and facilitates ER export in mammalian cells. PMID: 20679433
  4. p125 is a mammalian-specific component of ER exit sites and participates in the organization of this compartment PMID: 15623529
Subcellular Location
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum.
Protein Families
PA-PLA1 family
Tissue Specificity
Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle.
Database Links

HGNC: 17018

OMIM: 617852

KEGG: hsa:11196

STRING: 9606.ENSP00000358071

UniGene: Hs.435004

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