SEPT14 Antibody

Code CSB-PA778700
Size US$297
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  • Western blot analysis of extracts from NIH/3T3 cells, using SEPT14 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SEPT14 Polyclonal antibody
Uniprot No.
Target Names
SEPT14
Alternative Names
FLJ44060 antibody; SEP14_HUMAN antibody; SEPT 14 antibody; Sept14 antibody; Septin 14 antibody; Septin-14 antibody; Septin14 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from C-terminal of Human SEPT14.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Filament-forming cytoskeletal GTPase (Probable). Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development. Plays a role in sperm head formation during spermiogenesis, potentially via facilitating localization of ACTN4 to cell filaments.
Gene References into Functions
  1. The three SEPT14 SNPs defined a protective haplotype which significantly reduced the risk for Parkinson disease was found to be expressed in the brain. PMID: 27115672
  2. SEPT14 maps to 7p11.2 and includes a conserved GTPase domain and a predicted carboxy-terminus coiled-coil domain characteristic of other septins. PMID: 17922164
Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Perikaryon. Cytoplasm, perinuclear region. Cytoplasmic vesicle, secretory vesicle, acrosome.
Protein Families
TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
Tissue Specificity
Testis-specific (at protein level).
Database Links

HGNC: 33280

OMIM: 612140

KEGG: hsa:346288

STRING: 9606.ENSP00000373627

UniGene: Hs.453629

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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